CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
Synonyms:
C8orf61, EPMR
Species:
Human CLN8 (2055), Mouse Cln8 (26889), Rat Cln8 (306619), Zebrafish cln8 (100136870), cow CLN8 (530874), domestic cat CLN8 (101100714), dog CLN8 (488558), chicken CLN8 (421902), sheep CLN8 (101104038), naked mole-rat Cln8 (101702192)
UniProtKB ID:
Gene ID:
- Human(2055) Summary: This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2008]
- Mouse(26889) ceroid-lipofuscinosis, neuronal 8
- Rat(306619) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- Zebrafish(100136870) ceroid-lipofuscinosis, neuronal 8
- cow(530874) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- domestic cat(101100714) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- dog(488558) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- chicken(421902) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- sheep(101104038) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- naked mole-rat(101702192) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
- domestic guinea pig(100717237) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CLN8 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human
Application
western blot
esiRNA
Product Number
Description
Species