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CLN8

ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)

Synonyms:
C8orf61, EPMR
Species:
UniProtKB ID:
Gene ID:
  • Human(2055) Summary: This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2008]
  • Mouse(26889) ceroid-lipofuscinosis, neuronal 8
  • Rat(306619) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • Zebrafish(100136870) ceroid-lipofuscinosis, neuronal 8
  • cow(530874) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • domestic cat(101100714) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • dog(488558) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • chicken(421902) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • sheep(101104038) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • naked mole-rat(101702192) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
  • domestic guinea pig(100717237) ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CLN8 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CLN8,
Species
human
MISSION® esiRNA, targeting mouse Cln8,
Species
mouse
MISSION® esiRNA, targeting human CLN8 (2),
Species
human