CXCR4
chemokine (C-X-C motif) receptor 4
Synonyms:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Species:
Human CXCR4 (7852), Mouse Cxcr4 (12767), Rat Cxcr4 (60628), chicken CXCR4 (395324), domestic cat CXCR4 (493676), dog CXCR4 (483900), cow CXCR4 (281736), naked mole-rat Cxcr4 (101699254), domestic guinea pig Cxcr4 (100731341), sheep CXCR4 (443532)
UniProtKB ID:
Gene ID:
- Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(12767) chemokine (C-X-C motif) receptor 4
- Rat(60628) chemokine (C-X-C motif) receptor 4
- chicken(395324) chemokine (C-X-C motif) receptor 4
- domestic cat(493676) chemokine (C-X-C motif) receptor 4
- dog(483900) chemokine (C-X-C motif) receptor 4
- cow(281736) chemokine (C-X-C motif) receptor 4
- naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
- domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
- sheep(443532) neuropeptide Y receptor type 3
- Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CXCR4, (N-terminal) antibody produced in mouse, clone 2G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
western blot
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
flow cytometry
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-C-X-C Chemokine Receptor 4 Antibody, extracellular loop, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
western blot
Anti-C-X-C Chemokine Receptor 4 Antibody, NT, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CXCR-4, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Proteins
Product Number
Description
Species
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Species
human