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HARS2

histidyl-tRNA synthetase 2, mitochondrial

Synonyms:
HARSL, HARSR, HO3, PRLTS2
Species:
UniProtKB ID:
Gene ID:
  • Human(23438) Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(70791) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • Rat(307491) histidyl-tRNA synthetase 2, mitochondrial
  • chicken(768802) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • domestic cat(101098429) histidyl-tRNA synthetase 2, mitochondrial
  • cow(615182) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • dog(478035) histidyl-tRNA synthetase 2, mitochondrial (putative)
  • domestic guinea pig(100730771) histidyl-tRNA synthetase 2, mitochondrial
  • naked mole-rat(101713772) histidyl-tRNA synthetase 2, mitochondrial
  • sheep(101121599) histidyl-tRNA synthetase 2, mitochondrial

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HARS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Hars2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HARS2,
Species
human
MISSION® esiRNA, targeting mouse Hars2,
Species
mouse
MISSION® esiRNA, targeting human DTD1,
Species
human