HDAC8
histone deacetylase 8
동의어:
CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
종:
Human HDAC8 (55869), Mouse Hdac8 (70315), Rat Hdac8 (363481), Zebrafish hdac8 (406740), cow HDAC8 (540666), domestic cat HDAC8 (101096383), dog HDAC8 (480957), chicken HDAC8 (422182), domestic guinea pig Hdac8 (100721893), naked mole-rat Hdac8 (101697998)
UniProtKB ID:
Clone ID:
- Human(55869) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(70315) histone deacetylase 8
- Rat(363481) histone deacetylase 8
- Zebrafish(406740) histone deacetylase 8
- cow(540666) histone deacetylase 8
- domestic cat(101096383) histone deacetylase 8
- dog(480957) histone deacetylase 8
- chicken(422182) histone deacetylase 8
- domestic guinea pig(100721893) histone deacetylase 8
- naked mole-rat(101697998) histone deacetylase 8
- sheep(101110121) histone deacetylase 8
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Antibodies
Product Number
설명
종별 반응성
응용분야
Anti-HDAC8 Antibody, serum, Upstate®,
종별 반응성
human, mouse
응용분야
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Histone Deacetylase 8 (HDAC8) antibody produced in mouse, 2.0-2.5 mg/mL, clone HDAC8-48, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
microarray
western blot
microarray
western blot
Anti-phospho-HDAC8 (pSer39) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
immunohistochemistry
[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Product Number
설명
종
HDAC-8 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
종
human