NDE1
nudE neurodevelopment protein 1
Synonyms:
HOM-TES-87, LIS4, NDE, NUDE, NUDE1
Species:
Human NDE1 (54820), Mouse Nde1 (67203), Rat Nde1 (83836), Zebrafish nde1 (566146), chicken NDE1 (416597), cow NDE1 (508088), domestic cat NDE1 (101098423), dog NDE1 (100684378), domestic guinea pig Nde1 (100714890), naked mole-rat Nde1 (101720925)
UniProtKB ID:
Gene ID:
- Human(54820) Summary: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
- Mouse(67203) nuclear distribution gene E homolog 1 (A nidulans)
- Rat(83836) nudE neurodevelopment protein 1
- Zebrafish(566146) nudE nuclear distribution gene E homolog 1 (A. nidulans)
- chicken(416597) nudE nuclear distribution E homolog 1 (A. nidulans)
- cow(508088) nudE nuclear distribution gene E homolog 1 (A. nidulans)
- domestic cat(101098423) nudE nuclear distribution E homolog 1 (A. nidulans)
- dog(100684378) nudE nuclear distribution E homolog 1 (A. nidulans)
- domestic guinea pig(100714890) nudE nuclear distribution E homolog 1 (A. nidulans)
- naked mole-rat(101720925) nudE nuclear distribution E homolog 1 (A. nidulans)
- sheep(101114156) nudE nuclear distribution E homolog 1 (A. nidulans)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NDE1 antibody produced in mouse, clone 2G11-1C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-NDE1 Mouse mAb (2G11-1C11), liquid, clone 2G11-1C11, Calbiochem®,
Species Reactivity
human
Application
Anti-NDE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot