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PIM1

pim-1 oncogene

Synonyms:
PIM
Species:
UniProtKB ID:
Gene ID:
  • Human(5292) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Mouse(18712) proviral integration site 1
  • Rat(24649) pim-1 oncogene
  • Zebrafish(58054) pim-1 oncogene
  • domestic cat(493888) pim-1 oncogene
  • Horse(100053898) pim-1 oncogene
  • chicken(100858838) pim-1 oncogene
  • dog(481772) pim-1 oncogene
  • cow(281402) pim-1 oncogene
  • sheep(100272002) pim-1 oncogene
  • domestic guinea pig(100724588) pim-1 oncogene
  • naked mole-rat(101706236) pim-1 oncogene

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-PIM1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
western blot
Anti-PIM1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-PIM1 antibody produced in mouse, clone 6A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

Proteins

Product Number
Description
Species
PIM1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PIM1,
Species
human
MISSION® esiRNA, targeting mouse Pim1,
Species
mouse