PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
Synonymes:
PKACA
Espèce(s):
Human PRKACA (5566), Mouse Prkaca (18747), Rat Prkaca (25636), naked mole-rat Prkaca (101707235), domestic guinea pig Prkaca (100735694), cow PRKACA (282322), sheep PRKACA (443094), Horse PRKACA (100064302), domestic cat PRKACA (101090494), dog PRKACA (403556)
ID UniProtKB:
ID du gène:
- Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
- Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
- naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
- domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
- cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
- sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
- Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
- domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha
- dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
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Antibodies
Product Number
Description
Espèces réactives
Application
Anti-PKA α antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PRKACA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-PKA C-α Antibody, clone 2E17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
ANTI-PKA C-ALPHA/PKA C-BETA(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Espèce(s)
Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt, ≥90% (HPLC), lyophilized powder,
Espèce(s)
mouse, rat, human
Proteins
Product Number
Description
Espèce(s)
Protein Kinase A catalytic subunit human, >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Espèce(s)
human
PKA Protein, Recombinant, 10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
Espèce(s)