SOST
sclerostin
Synonyms:
CDD, VBCH
Species:
Human SOST (50964), Mouse Sost (74499), Rat Sost (80722), Zebrafish sost (100000500), chicken SOST (429784), domestic cat SOST (101083725), dog SOST (490948), domestic guinea pig Sost (100730713), naked mole-rat Sost (101719889), cow SOST (282880)
UniProtKB ID:
Gene ID:
- Human(50964) Summary: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]
- Mouse(74499) sclerostin
- Rat(80722) sclerostin
- Zebrafish(100000500) sclerostin
- chicken(429784) sclerostin
- domestic cat(101083725) sclerostin
- dog(490948) sclerostin
- domestic guinea pig(100730713) sclerostin
- naked mole-rat(101719889) sclerostin
- cow(282880) sclerostin
- sheep(101114123) sclerostin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-SOST(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
ANTI-SOST(N-TERMINAL) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-Sclerostin Antibody, clone 7B6.1 | MABS445, culture supernatant, clone 7B6.1, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
ANTI-SOST (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-SOST (center) antibody produced in rabbit, Ig fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry