SPHK1
sphingosine kinase 1
Synonyms:
SPHK
Species:
Human SPHK1 (8877), Mouse Sphk1 (20698), Rat Sphk1 (170897), Thale Cress SPHK1 (828239), chicken SPHK1 (427803), dog SPHK1 (483329), domestic cat SPHK1 (101084918), Horse SPHK1 (100058875), cow SPHK1 (618605), sheep SPHK1 (101105263) ...More
UniProtKB ID:
Gene ID:
- Human(8877) Summary: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Mouse(20698) sphingosine kinase 1
- Rat(170897) sphingosine kinase 1
- Thale Cress(828239) sphingosine kinase 1
- chicken(427803) sphingosine kinase 1
- dog(483329) sphingosine kinase 1
- domestic cat(101084918) sphingosine kinase 1
- Horse(100058875) sphingosine kinase 1
- cow(618605) sphingosine kinase 1
- sheep(101105263) sphingosine kinase 1
- domestic guinea pig(100727266) sphingosine kinase 1
- naked mole-rat(101711606) sphingosine kinase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SPHK1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-SPHK1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-SPHK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
SPHK1, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Sphingosine kinase 1 Active human, recombinant, expressed in baculovirus, ≥80% (SDS-PAGE),
Species
human
Sphingosine kinase 1a Active from mouse, recombinant, expressed in baculovirus, ≥70% (SDS-PAGE),
Species
human