P9391

Procainamide hydrochloride

• Synonym(s): 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide
• Linear Formula: H₂NC₆H₄CONHCH₂CH₂N(C₂H₅)₂·HCl
• CAS Number: 614-39-1
• Molecular Weight: 271.79
• Beilstein: 3729517
• EC Number: 210-381-7
• MDL number: MFCD00012998
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277864

Properties

• form: powder
• mp: 167-169 °C (lit.)
• solubility: H₂O: soluble; ethanol: soluble
• originator: Bristol-Myers Squibb
• SMILES string: Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1
• InChI: 1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
• InChI key: ABTXGJFUQRCPNH-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

Biochem/physiol Actions

Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Na⁺ channel blocker and Class IA anti-arrhythmic.

Features and Benefits

This compound is a featured product for ADME Tox and Gene Regulation research. Discover more featured ADME Tox and Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves