C7642

Concanavalin A from Canavalia ensiformis (Jack bean)

FITC conjugate, Type IV, lyophilized powder

• Sinônimo(s): ConA
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: Canavalia ensiformis
• Nível de qualidade: 200
• conjugado: FITC conjugate
• tipo: Type IV
• Formulário: lyophilized powder
• composição: Protein, 5-15% biuret
• Extensão da rotulagem: 3-6 mol FITC per mol protein
• Impurezas: Carbohydrate, essentially free
• temperatura de armazenamento: −20°C

Descrição

Aplicação

For the fluorescent detection of glycoproteins containing α−D-mannose or α−D-glucose

Ações bioquímicas/fisiológicas

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Embalagem

Package size based on protein content

forma física

Lyophilized powder containing phosphate buffer salts and NaCl

Nota de análise

Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca²⁺ and Mn²⁺ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P280 - P302 + P352
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves