L1012

Ácido linoleico

liquid, BioReagent, suitable for cell culture

• Sinônimo(s): Ácido cis-9,cis-12-octadecadienoico
• Fórmula linear: CH₃(CH₂)₄CH=CHCH₂CH=CH(CH₂)₇CO₂H
• CAS Number: 60-33-3
• Peso molecular: 280.45
• Beilstein: 1727101
• Número CE: 200-470-9
• Número MDL: MFCD00064241
• Código UNSPSC: 12352211
• eCl@ss: 32190102
• ID de substância PubChem: 24896270
• NACRES: NA.75

Propriedades

• fonte biológica: plant (Safflower oil)
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥98%
• Formulário: liquid
• técnica(s): cell culture | mammalian: suitable
• índice de refração: n20/D 1.466 (lit.)
• p.e.: 229-230 °C/16 mmHg (lit.)
• pf: −5 °C (lit.)
• solubilidade: NaOH: 1 M; ethanol: soluble
• densidade: 0.902 g/mL at 25 °C (lit.)
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
• chave InChI: OYHQOLUKZRVURQ-HZJYTTRNSA-N
• Informações sobre genes: human ... SOAT1(6646), SOAT2(8435)

Descrição

Descrição geral

Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.

Aplicação

Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.

Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).

Ações bioquímicas/fisiológicas

O ácido linoleico aumenta a proliferação celular e a expressão gênica de PPARα e seus genes-alvo, como acil-CoA oxidase, em hepatócitos primários de pato .

Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Embalagem

Sealed ampule.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)