T2320

T0901317

≥98%

• Sinônimo(s): N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide
• Fórmula empírica (Notação de Hill): C₁₇H₁₂NSO₃F₉
• CAS Number: 293754-55-9
• Peso molecular: 481.33
• Número MDL: MFCD03412028
• Código UNSPSC: 12352106
• ID de substância PubChem: 24900032
• NACRES: NA.25

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥98%
• peso molecular: 481.3
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c2ccccc2)(C(F)(F)F)C(F)(F)F
• InChI: 1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
• chave InChI: SGIWFELWJPNFDH-UHFFFAOYSA-N
• Informações sobre genes: human ... ABCA1(19), NR1H2(7376), NR1H3(10062)

Descrição

Aplicação

T0901317 has been used in LXR agonist study in order to observe the expression of all dietary cholesterol-regulated genes in mice. It has also been used to stimulate the radiolabeled peritoneal macrophages from WT (wildtype) and Tg (transgenic) mice for cellular cholesterol efflux assay.

Ações bioquímicas/fisiológicas

LXR agonist whose treatment results in an LXR-dependent up-regulation of ABC1 gene expression

T0901317 can prevent the secretion of insulin by acting on the metabolism of mitochondria.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)