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104051

Sigma-Aldrich

Picolinamide

98%

Synonym(s):

2-Pyridinecarboxamide

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About This Item

Empirical Formula (Hill Notation):
C6H6N2O
CAS Number:
Molecular Weight:
122.12
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

98%

mp

110 °C (dec.) (lit.)

functional group

amide

SMILES string

NC(=O)c1ccccn1

InChI

1S/C6H6N2O/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9)

InChI key

IBBMAWULFFBRKK-UHFFFAOYSA-N

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1 of 4

This Item
SML0345SML0494SML1088
A 887826 ≥98% (HPLC)

SML0345

A 887826

SRPIN340 ≥98% (HPLC)

SML1088

SRPIN340

assay

98%

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

110 °C (dec.) (lit.)

mp

-

mp

-

mp

-

functional group

amide

functional group

-

functional group

-

functional group

-

Application

Picolinamide was used as template in preparation of molecular imprinting polymer[1]. Picolinamide was used in a study to evaluate kinetics and mechanism of liberation of picolinamide from chromium(III)-picolinamide complexes in HClO4[2].

Biochem/physiol Actions

Picolinamide is potential inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells[3]. Picolinamide acts as bidentate ligand and forms complexes with lanthanide nitrates, thiocyanates and perchlorates[4].

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
H Yamamoto et al.
Biochemical and biophysical research communications, 95(1), 474-481 (1980-07-16)
Lanthanide complexes with picolinamide.
Condorelli G, et al.
J. Inorg. Nucl. Chem., 36(12), 3763-3766 (1974)
Ángel Manu Martínez et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(48), 11669-11676 (2017-06-22)
A practical picolinamide-directed C-H functionalization/alkyne annulation of benzylamine derivatives enabling access to the previously elusive 1,4-dihydroisoquinoline skeleton was developed using molecular O
Study properties of molecular imprinting polymer using a computational approach.
Wu L, et al.
Analyst, 128(7), 944-949 (2003)
Jason L Atkins et al.
Journal of the American Chemical Society, 134(33), 13546-13549 (2012-08-07)
Tris-arenes based on either isophthalic acid or 2,6-dipicolinic acid have been known for more than a decade to bind anions. Recent studies have also demonstrated their ability to transport various ions through membranes. In this report, we demonstrate two important

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