108456

Trimethyl orthoformate

99%

• Synonym(s): Trimethoxymethane
• Linear Formula: CH(OCH₃)₃
• CAS Number: 149-73-5
• Molecular Weight: 106.12
• Beilstein: 969215
• EC Number: 205-745-7
• MDL number: MFCD00008483
• UNSPSC Code: 12352100
• eCl@ss: 39021015
• PubChem Substance ID: 24846805
• NACRES: NA.22

Properties

• vapor density: 3.67 (vs air)
• Quality Level: 200
• vapor pressure: 23.5 mmHg ( 20 °C); 40 mmHg ( 30 °C); 57 mmHg ( 40 °C)
• Assay: 99%
• expl. lim.: 5.1 %
• refractive index: n20/D 1.379 (lit.)
• bp: 101-102 °C (lit.)
• density: 0.97 g/mL at 25 °C (lit.)
• functional group: ether
• SMILES string: COC(OC)OC
• InChI: 1S/C4H10O3/c1-5-4(6-2)7-3/h4H,1-3H3
• InChI key: PYOKUURKVVELLB-UHFFFAOYSA-N

Description

General description

Trimethyl orthoformate is an effective solvent for thallium(III) nitrate-mediated oxidations. It undergoes acid catalyzed reaction with 6-(N-D-ribitylanilino) uracils to form 8-demethyl-8-hydroxy-5-deazariboflavins.

Application

Trimethyl orthoformate was used as dehydrating agent in the preparation of surface-modified colloidal silica nanoparticles.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 55.4 °F - closed cup
• Flash Point(C): 13 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves