114286

4-Hydroxyphenylpyruvic acid

98%

• Synonym(s): 3-(4-Hydroxyphenyl)-2-oxopropanoic acid
• Linear Formula: HOC₆H₄CH₂COCO₂H
• CAS Number: 156-39-8
• Molecular Weight: 180.16
• Beilstein: 2691632
• EC Number: 205-852-9
• MDL number: MFCD00002591
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847164
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: solid
• mp: 219-220 °C (dec.) (lit.)
• solubility: ethanol: soluble 50 mg/mL
• functional group: carboxylic acid; ketone
• SMILES string: OC(=O)C(=O)Cc1ccc(O)cc1
• InChI: 1S/C9H8O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,10H,5H2,(H,12,13)
• InChI key: KKADPXVIOXHVKN-UHFFFAOYSA-N

Description

General description

4-hydroxyphenylpyruvic acid can be determined in pork meat and Iberian ham samples by a sensitive method of multiple reaction monitoring (MRM) by mass spectrometry.

Application

<ul>
<li><strong>Identification of serum biomarkers of ischemic stroke:</strong>4-Hydroxyphenylpyruvic acid is used as a potential diagnostic biomarker in the study to distinguish hypertensive ischemic stroke (IS) patients from both healthy individuals and those with hypertension (Zhao et al., 2023).</li>
</ul>

Preparation Note

50 gm of 4-Hydroxyphenylpyruvic acid dissolves in 1 mL of ethanol to yield a clear, light yellow solution.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319
• Precautionary Statements: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves