167169

3-Bromo-1-propanol

97%

• Synonym(s): Trimethylene bromohydrin
• Linear Formula: Br(CH₂)₃OH
• CAS Number: 627-18-9
• Molecular Weight: 138.99
• Beilstein: 969160
• EC Number: 210-986-6
• MDL number: MFCD00002942
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850196
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.488 (lit.)
• bp: 62 °C/5 mmHg (lit.)
• density: 1.537 g/mL at 25 °C (lit.)
• functional group: bromo; hydroxyl
• storage temp.: 2-8°C
• SMILES string: OCCCBr
• InChI: 1S/C3H7BrO/c4-2-1-3-5/h5H,1-3H2
• InChI key: RQFUZUMFPRMVDX-UHFFFAOYSA-N

Description

General description

Reaction between 3-bromo-1-propanol, phenol and a series of phenols having substituents in 4-position has been studied in micellar media and in microemulsions based on cationic or a nonionic surfactant.

3-Bromo-1-propanol is an electrophile used as a substrate in nucleophilic substitution reactions and in the redox polymerization.

Application

3-Bromo-1-propanol was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and molten salt-polymers. It was used in the synthesis of chiral, quaternary prolines via cyclization of quaternary amino acids.

Recently used as a grafting agent in the synthesis of recyclable reagents for Swern oxidation

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 149.0 °F - closed cup
• Flash Point(C): 65 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves