183075

1-Methylisatin

97%

• Synonym(s): N-Methylindoline-2,3-dione, NSC 42449
• Empirical Formula (Hill Notation): C₉H₇NO₂
• CAS Number: 2058-74-4
• Molecular Weight: 161.16
• EC Number: 218-164-9
• MDL number: MFCD00005812
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851030
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• mp: 130-133 °C (lit.)
• functional group: ketone
• SMILES string: CN1C(=O)C(=O)c2ccccc12
• InChI: 1S/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3
• InChI key: VCYBVWFTGAZHGH-UHFFFAOYSA-N
• Gene Information: human ... CASP3(836)

Description

General description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

Application

• Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
• Reactant for regioselective preparation of spirocyclic oxindole-butenolides
• Reactant for synthesis of spiro-oxindoles
• Reactant for preparation of unsymmetrical oxindoles
• Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
• Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H315,H318,H335
• Precautionary Statements: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves