213497

2-Hydroxycarbazole

97%

• Synonym(s): 2-Carbazolol
• Empirical Formula (Hill Notation): C₁₂H₉NO
• CAS Number: 86-79-3
• Molecular Weight: 183.21
• Beilstein: 135859
• EC Number: 201-699-7
• MDL number: MFCD00004962
• UNSPSC Code: 12352100
• PubChem Substance ID: 24852786
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 97%
• form: solid
• mp: 270-273 °C (lit.)
• SMILES string: Oc1ccc2c(c1)[nH]c3ccccc23
• InChI: 1S/C12H9NO/c14-8-5-6-10-9-3-1-2-4-11(9)13-12(10)7-8/h1-7,13-14H
• InChI key: GWPGDZPXOZATKL-UHFFFAOYSA-N

Description

General description

2-Hydroxycarbazole is a compound structurally related to the Ca²⁺-mobilizing marine toxin, 9-methyl-7-bromoeudistomin. Room temperature electronic absorption and fluorescence spectra of 2-hydroxycarbazole has been studied in concentrated aqueous potassium hydroxide solutions. It undergoes chemoselective N-alkylation using NaH as a base in a THF-DMF solvent system.

Application

2-Hydroxycarbazole was used in the synthesis of isochromene fused carbazol, (4aS,13bR)-2,5,5-trimethyl-3,4,4a,5,8,13b-hexahydroisochromeno[3,4-b]carbazole.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves