218898

5-(Dimethylamino)-1-naphthalenesulfonamide

99%

• Synonym(s): DNSA, Dansyl amide
• Linear Formula: (CH₃)₂NC₁₀H₆SO₂NH₂
• CAS Number: 1431-39-6
• Molecular Weight: 250.32
• Beilstein: 2217203
• EC Number: 215-854-1
• MDL number: MFCD00004000
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853099
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99%
• mp: 218-221 °C (lit.)
• fluorescence: λ_ex 280 nm; λ_em 470 nm (bound to carbon anhydrase); λ_em 580 in ethanol
• functional group: amine
• SMILES string: CN(C)c1cccc2c(cccc12)S(N)(=O)=O
• InChI: 1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)
• InChI key: TYNBFJJKZPTRKS-UHFFFAOYSA-N

Description

Application

5-(Dimethylamino)-1-naphthalenesulfonamide (DNSA) was used as starting reagent in the synthesis of 2,6-disubstituted pyridines, 6-substituted 2,2′-bipyridines and 6,6′-disubstituted 2,2′-bipyridines. It was also used as fluorescent probe in the determination of concentration of human carbonic anhydrase II-DNSA in solutions.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves