233412

Ethyl (hydroxyimino)cyanoacetate

97%, for peptide synthesis

• Synonym(s): Ethyl cyano(hydroxyimino)acetate, Ethyl cyanoglyoxalate-2-oxime, Ethyl isonitrosocyanoacetate
• Linear Formula: NCC(=NOH)CO₂C₂H₅
• CAS Number: 3849-21-6
• Molecular Weight: 142.11
• Beilstein: 774783
• EC Number: 223-351-3
• MDL number: MFCD00002112
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853975
• NACRES: NA.22

Properties

• Product Name: Ethyl (hydroxyimino)cyanoacetate, 97%
• Quality Level: 200
• Assay: 97%
• form: solid
• mp: 130-132 °C (lit.)
• application(s): peptide synthesis
• functional group: amine; ester; nitrile; oxime
• SMILES string: CCOC(=O)C(=N\O)\C#N
• InChI: 1S/C5H6N2O3/c1-2-10-5(8)4(3-6)7-9/h9H,2H2,1H3/b7-4+
• InChI key: LCFXLZAXGXOXAP-QPJJXVBHSA-N

Description

General description

Ethyl (hydroxyimino)cyanoacetate is a potential replacement for zobenzotriazole and benzotriazole derivatives used in peptide synthesis.

Ethyl (hydroxyimino)cyanoacetate is also called as Oxyma. It is a highly efficient greener alternative for the amide and peptide synthesis.

Application

Ethyl (hydroxyimino)cyanoacetate has been used as an additive for the carbodiimide-mediated amide bond formation during established peptide synthesis method.For peptide synthesis grade material, please see product 851086.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves