245771

Isobutyric anhydride

97%

• Synonym(s): 2-Methylpropionic anhydride
• Linear Formula: (CH₃)₂CHCO₂COCH(CH₃)₂
• CAS Number: 97-72-3
• Molecular Weight: 158.19
• Beilstein: 386267
• EC Number: 202-603-6
• MDL number: MFCD00008913
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854757
• NACRES: NA.22

Properties

• vapor density: 5.45 (vs air)
• Quality Level: 200
• vapor pressure: 10 mmHg ( 67 °C)
• Assay: 97%
• form: liquid
• autoignition temp.: 624 °F
• expl. lim.: 1.09 %, 87 °F; 7.7 %, 127 °F
• refractive index: n20/D 1.406 (lit.)
• bp: 182 °C (lit.)
• mp: −56 °C (lit.)
• density: 0.954 g/mL at 25 °C (lit.)
• functional group: anhydride; ester
• SMILES string: CC(C)C(=O)OC(=O)C(C)C
• InChI: 1S/C8H14O3/c1-5(2)7(9)11-8(10)6(3)4/h5-6H,1-4H3
• InChI key: LSACYLWPPQLVSM-UHFFFAOYSA-N

Description

General description

The mechanism of esterification of 1-(1-naphthyl)ethanol by isobutyric anhydride with 4-pyrrolidinopyridine as catalyst was studied.

Application

Isobutyric anhydride was used in the synthesis of 4-O-isobutyryl derivative via reaction with octyl β-D-glucopyranoside in the presence of C₂-symmetric chiral 4-pyrrolidinopyridine as a catalyst.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301 + H311,H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P361 + P364 - P405
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 154.4 °F - closed cup
• Flash Point(C): 68 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves