269964

4-Nitroindole

97%

• Empirical Formula (Hill Notation): C₈H₆N₂O₂
• CAS Number: 4769-97-5
• Molecular Weight: 162.15
• MDL number: MFCD00010056
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856183
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• mp: 205-207 °C (lit.)
• SMILES string: [O-][N+](=O)c1cccc2[nH]ccc12
• InChI: 1S/C8H6N2O2/c11-10(12)8-3-1-2-7-6(8)4-5-9-7/h1-5,9H
• InChI key: LAVZKLJDKGRZJG-UHFFFAOYSA-N

Description

Application

4-Nitroindole was used in the synthesis of 1,3,4,5-tetrahydropyrrolo-[4,3,2-de]quinoline.

Reactant for preparation of:

• Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Meridianin derivatives as protein kinase (PKC) inhibitors and vitro antiproliferative agents
• Anti-angiogenic agents
• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes
• Biologically active indoles
• CGRP receptor antagonists
• Nucleosides
• CB2 cannabinoid receptor ligands

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves