303585

2-Amino-5-nitrophenol

• Synonym(s): 2-Hydroxy-4-nitroaniline, 3-Hydroxy-4-aminonitrobenzene, 3-Nitro-6-aminophenol, 5-Nitro-2-amino-1-hydroxybenzene, 5-Nitro-2-aminophenol, NSC 7087
• Linear Formula: H₂NC₆H₃(NO₂)OH
• CAS Number: 121-88-0
• Molecular Weight: 154.12
• Beilstein: 972974
• EC Number: 204-503-8
• MDL number: MFCD00007692
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858130
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• mp: 198-202 °C (dec.) (lit.)
• functional group: nitro
• SMILES string: Nc1ccc(cc1O)[N+]([O-])=O
• InChI: 1S/C6H6N2O3/c7-5-2-1-4(8(10)11)3-6(5)9/h1-3,9H,7H2
• InChI key: DOPJTDJKZNWLRB-UHFFFAOYSA-N

Description

Application

2-Amino-5-nitrophenol was used:

• as starting material in the synthesis of series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides
• as semipermanent (nonoxidative) hair colorant and as toner in permanent (oxidative) hair dye products
• in synthesis of series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones, anticonvulsant agents

Reactant for:

• Diazotation and coupling reactions
• Preparation of biologically and pharmacologically active molecules

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves