349984

2-Bromo-4-methylpyridine

97%

• Empirical Formula (Hill Notation): C₆H₆BrN
• CAS Number: 4926-28-7
• Molecular Weight: 172.02
• MDL number: MFCD00082590
• UNSPSC Code: 12352100
• PubChem Substance ID: 24861720
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 97%
• form: liquid
• refractive index: n20/D 1.561 (lit.)
• bp: 87 °C/10 mmHg (lit.)
• density: 1.545 g/mL at 25 °C (lit.)
• functional group: bromo
• SMILES string: Cc1ccnc(Br)c1
• InChI: 1S/C6H6BrN/c1-5-2-3-8-6(7)4-5/h2-4H,1H3
• InChI key: LSZMVESSGLHDJE-UHFFFAOYSA-N

Description

Application

2-Bromo-4-methylpyridine may be used:

• in the total synthesis of ocular age pigment A2-E (2 equiv of retinal (vitamin A) and 1 equiv of ethanolamine)
• in the preparation of methoxy-2-(2-pyridyl)indoles
• in the preparation of 2-(2′,4′-difluorophenyl)-4-methylpyridine, via a Suzuki coupling reaction with 2,4-difluorophenylboronic acid

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves