423955

Methyl 2-methylglycidate

99%

• Empirical Formula (Hill Notation): C₅H₈O₃
• CAS Number: 58653-97-7
• Molecular Weight: 116.12
• MDL number: MFCD00198125
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866542
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 99%
• refractive index: n20/D 1.418 (lit.)
• bp: 62-65 °C/32 mmHg (lit.)
• density: 1.097 g/mL at 25 °C (lit.)
• functional group: ester; ether
• SMILES string: COC(=O)C1(C)CO1
• InChI: 1S/C5H8O3/c1-5(3-8-5)4(6)7-2/h3H2,1-2H3
• InChI key: OSYXXQUUGMLSGE-UHFFFAOYSA-N

Description

General description

Methyl 2-methylglycidate (methyl 2-methyloxirane-2-carboxylate) is an ester derived epoxide. It is reported to be formed by the reaction of methyl pyruvate with diazomethane. It is formed as an intermediate in the synthesis of 1,2,4-oxadiazole derivatives.

Application

Methyl 2-methylglycidate may be used in the synthesis of:

• 2-methyl-2-hydroxy-1-propanol
• 2,3-dihydroxy-2-methyl propionic acid
• methyl 2-hydroxy-3-((4-methoxyphenyl)sulfonyl)-2-methylpropanoate

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H335
• Precautionary Statements: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 129.2 °F - closed cup
• Flash Point(C): 54 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves