456268

(S)-(−)-Glycidyl trityl ether

98%

• Empirical Formula (Hill Notation): C₂₂H₂₀O₂
• CAS Number: 129940-50-7
• Molecular Weight: 316.39
• MDL number: MFCD00273373
• UNSPSC Code: 12352005
• PubChem Substance ID: 24869145
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• form: solid
• optical activity: [α]20/D −10.5°, c = 1 in chloroform
• optical purity: ee: 98% (GLC)
• mp: 99-102 °C (lit.)
• functional group: ether; phenyl
• SMILES string: C1O[C@@H]1COC(c2ccccc2)(c3ccccc3)c4ccccc4
• InChI: 1S/C22H20O2/c1-4-10-18(11-5-1)22(24-17-21-16-23-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17H2/t21-/m0/s1
• InChI key: XFSXUCMYFWZRAF-NRFANRHFSA-N

Description

Application

(S)-(-)-Glycidyl trityl ether may be used to prepare N-(p-alkoxy)benzoyl-2-methylindole-4-acetic acid analogs, which are potent prostaglandin D₂ (PGD₂) receptor antagonists. It may also be used as a starting material in the multi-step synthesis of (-)-actisonitrile.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves