514101

1,2,4-Butanetricarboxylic acid

• Synonym(s): 1,2,4-Tricarboxybutane, 3-Carboxyhexanedioic acid, NSC 60127, NSC 8447
• Linear Formula: HO₂CCH₂CH₂CH(CO₂H)CH₂CO₂H
• CAS Number: 923-42-2
• Molecular Weight: 190.15
• MDL number: MFCD00152304
• UNSPSC Code: 12352100
• PubChem Substance ID: 24873740
• NACRES: NA.22

Properties

• Quality Level: 100
• mp: 117-120 °C (lit.)
• functional group: carboxylic acid
• SMILES string: OC(=O)CCC(CC(O)=O)C(O)=O
• InChI: 1S/C7H10O6/c8-5(9)2-1-4(7(12)13)3-6(10)11/h4H,1-3H2,(H,8,9)(H,10,11)(H,12,13)
• InChI key: LOGBRYZYTBQBTB-UHFFFAOYSA-N
• Gene Information: human ... FOLH1(2346)

Description

Application

Biological activity:

• Tetracoordinate Ni(II) binding by E. coli NikA employs His416 residue in conjunction with three carboxylate ligands from butane-1,2,4-tricarboxylate (BTC)
• Potential inhibitor of glutamate carboxypeptidase II

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves