634492

4-Pyridinylboronic acid

90%

• Synonym(s): 4-Pyridineboronic acid, 4-Pyridylboronic acid
• Empirical Formula (Hill Notation): C₅H₆BNO₂
• CAS Number: 1692-15-5
• Molecular Weight: 122.92
• MDL number: MFCD01074545
• UNSPSC Code: 12352103
• PubChem Substance ID: 24882629
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 90%
• form: solid
• mp: >300 °C (lit.)
• storage temp.: −20°C
• SMILES string: OB(O)c1ccncc1
• InChI: 1S/C5H6BNO2/c8-6(9)5-1-3-7-4-2-5/h1-4,8-9H
• InChI key: QLULGIRFKAWHOJ-UHFFFAOYSA-N

Description

General description

4-Pyridinylboronic acid is commonly used as a reagent in cross-coupling reactions such as Suzuki-Miyaura cross-coupling.

Application

Reagent used for

• Palladium-catalyzed Suzuki-Miyaura coupling reactions
• Ligand-free palladium-catalyzed Suzuki coupling reaction under microwave irradation

Reagent used in Preparation of

• HIV-1 protease inhibitors
• Potential cancer threapeutics, such as PDK1 and protein kinase CK2 inhibitors

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves