733539

N-Boc-pyrrole-2-boronic acid MIDA ester

95%

• Synonym(s): 1-(tert-Butoxycarbonyl)pyrrole-2-boronic acid MIDA ester
• Empirical Formula (Hill Notation): C₁₄H₁₉BN₂O₆
• CAS Number: 1158984-94-1
• Molecular Weight: 322.12
• MDL number: MFCD18252677
• UNSPSC Code: 12352103
• PubChem Substance ID: 329764826
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 95%
• form: solid
• mp: 166-171 °C
• SMILES string: CN1CC(=O)OB(OC(=O)C1)c2cccn2C(=O)OC(C)(C)C
• InChI: 1S/C14H19BN2O6/c1-14(2,3)21-13(20)17-7-5-6-10(17)15-22-11(18)8-16(4)9-12(19)23-15/h5-7H,8-9H2,1-4H3
• InChI key: HASMDYSWFBSATG-UHFFFAOYSA-N

Description

Application

Suzuki Cross-Coupling with MIDA Boronates

N-Boc-pyrrole-2-boronic acid MIDA ester can be used:

• As a starting material for the synthesis of marine natural product pentabromopseudilin.
• To prepare 5,5′-(3,4-dihexylthiophene-2,5-diyl)bis(1H-pyrrole-2-carbaldehyde), a key intermediate for the synthesis of thiophene based novel macrocycles.
• As a substrate in the palladium-catalyzed one-pot meta arylation of bromo substituted 2-phenylpyridine.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable