791643C

18:1-d7 Lyso PC

Avanti Research^™ - A Croda Brand

• Synonym(s): 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine
• Empirical Formula (Hill Notation): C₂₆H₄₅D₇NO₇P
• CAS Number: 2097561-13-0
• Molecular Weight: 528.71
• MDL number: MFCD34647476
• UNSPSC Code: 41141825
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (791643C-1mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• concentration: 1 mg/mL (791643C-1mg)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

18:1-d7 Lyso PC 1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphocholine is a deuterated phospholipid. The lipid lysophosphatidylcholine is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylcholine (LPC) is derived from phosphatidylcholine by the action of enzyme phospholipase A2.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

18:1-d7 Lyso PC has been used:

• as an internal standard in high performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESIMS/MS) for the lipidomics analysis of bone marrow-derived macrophages
• as a component of extraction solvent for lipid isolation from biological samples
• as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)

Biochem/physiol Actions

Lysophosphatidylcholine (LPC). Elevated levels of LPC is associated with diabetes and cardiovascular diseases. LPC stimulates cytokines and is implicated in allergic disease. It also elicits lysis on membranes.

Packaging

5 mL Clear Glass Sealed Ampule (791643C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash