858125P

18:1 Lyso PG

1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

• Synonym(s): 1-oleoy-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); PG(18:1(9Z)/0:0); 110714
• Empirical Formula (Hill Notation): C₂₄H₄₆O₉PNa
• CAS Number: 326495-24-3
• Molecular Weight: 532.58
• MDL number: MFCD00674367
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (LPG; may contain up to 10% of the 2-LPG isomer, TLC)
• form: powder
• packaging: pkg of 1 × 1 g (858125P-1g); pkg of 5 × 100 mg (858125P-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 858125P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC(O)CO)=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C24H47O9P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(28)31-19-23(27)21-33-34(29,30)32-20-22(26)18-25;/h9-10,22-23,25-27H,2-8,11-21H2,1H3,(H,29,30);/q;+1/p-1/b10-9-;/t22?,23-;/m1./s1
• InChI key: STLDIXSFXILIFT-AXFOVFEGSA-M

Description

General description

18:1 Lyso phosphoglycerol is a lyso-phospholipid detergent. Lyso-phospholipids are synthesized in γ-proteobacteria. They are non bilayer- forming lipids, present in very minute amounts.

Application

18:1 Lyso PG may be used:

• for the preparation of liposomes
• to determine the effects of phosphoglycerol(PG) and cardiolipin (CL) in F0F1 ATPase c subunit (F0-c) transformation
• as an acyl acceptor to determine the substrate specificity of recombinant G0/G1 switch gene 2 (G0S2) for acyl acceptors

Biochem/physiol Actions

Lyso phosphoglycerol (Lyso PG) serves as a substrate for lysophosphatidylglycerol acyltransferase 1 (LPGAT1) for the synthesis of phosphoglycerol. Accumulation of lysophospholipids in bacterial membranes disturbs the membrane integrity due to its detergent-like physical property.

Packaging

5 mL Clear Glass Sealed Ampule (858125P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (858125P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids