LM1900

17:0-20:4 PI(3)P

Avanti Research^™ - A Croda Brand

• Synonym(s): 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′-phosphate) (ammonium salt)
• Empirical Formula (Hill Notation): C₄₆H₈₈N₂O₁₆P₂
• CAS Number: 1246304-67-5
• Molecular Weight: 987.14
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: powder
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• packaging: 1 ea of 1 × (with stopper and crimp cap (LM1900-1EA))
• application(s): lipidomics; metabolomics
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]
• InChI key: IOJKXWHTFCVKEI-DOKNWMIYSA-N

Description

General description

17:0-20:4 PI(3)P, phosphatidylinositol 3?phosphate, is the predominant phosphoinositide localized in endosomes and yeast vacuoles. It is synthesized by phosphatidylinositol 3?kinase (PI3K) from phosphatidylinositol.

Application

17:0-20:4 PI(3)P has been used as an internal standard for targeted lipidomic analysis.

Biochem/physiol Actions

17:0-20:4 PI(3)P plays a vital role in intracellular membrane trafficking and recruitment of effector proteins, which possess PI(3)P-binding motifs to membranes. It also regulates the formation of autophagosomes.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1900-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids