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172103

Sigma-Aldrich

Anaphase-Promoting Complex Inhibitor Negative Control, AAME

The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.

Synonym(s):

Anaphase-Promoting Complex Inhibitor Negative Control, AAME, AAME hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H18N4O3 · xHCl
CAS Number:
Molecular Weight:
230.26 (free base basis)
MDL number:
UNSPSC Code:
41106609
NACRES:
NA.77
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Quality Level

Assay

≥99% (TLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

N=C(NCCC[C@@H](C(OC)=O)NC(C)=O)N.[xHCl]

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This Item
172104324889182517
form

powder

form

solid

form

solid

form

solid

assay

≥99% (TLC)

assay

≥98% (HPLC)

assay

≥99% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

water: 50 mg/mL

solubility

DMSO: 50 mg/mL

solubility

DMSO: 10 mg/mL, yellow

solubility

DMSO: 50 mg/mL

General description

An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation.

Packaging

Packaged under inert gas

Warning

Toxicity: Regulatory Review (Z)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Zeng, X., et al. 2010. Cancer Cell18, 382.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of bacteriology, 188(11), 3796-3804 (2006-05-19)
The F(1)F(o)-ATP synthases of alkaliphilic bacteria exhibit latent ATPase activity, and for the thermoalkaliphile Bacillus sp. strain TA2.A1, this activity is intrinsic to the F(1) moiety. To study the mechanism of ATPase inhibition, we developed a heterologous expression system in

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