218746

Caspase-1 Inhibitor VI

≥95% (HPLC), powder, Caspase-1 inhibitor, Calbiochem^®

• Synonym(s): Caspase-1 Inhibitor VI, Z-YVAD-FMK
• Empirical Formula (Hill Notation): C₃₁H₃₉FN₄O₉
• Molecular Weight: 630.66
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Product Name: Caspase-1 Inhibitor VI, Caspase-1 Inhibitor VI, Z-YVAD-FMK, is a potent, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5.
• Quality Level: 100
• Assay: ≥95% (HPLC); ≥95% (TLC)
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• color: white
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A potent, cell-permeable and irreversible inhibitor of caspase-1 (ICE).

A potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5.

Biochem/physiol Actions

Cell permeable: yes

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Tyr-Val-Ala-Asp(OMe)-CH₂F*

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable