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8.18580

Sigma-Aldrich

Methoxymethyl-triphenylphosphonium chloride

for synthesis

Synonym(s):

Methoxymethyl-triphenylphosphonium chloride

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100 μG
MYR 1,723.00

MYR 1,723.00


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100 μG
MYR 1,723.00

About This Item

Linear Formula:
CH3OCH2P(C6H5)3Cl
CAS Number:
Molecular Weight:
342.80
MDL number:
UNSPSC Code:
12352107
EC Index Number:
223-664-5
NACRES:
NA.22

MYR 1,723.00


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A recombinant, preservative-free antibody is available for your target. Try ZRB1702

Request a Bulk Order
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vapor pressure

<1 hPa ( 20 °C)

Quality Level

form

powder

potency

1440 mg/kg LD50, oral (Rat)

reaction suitability

reaction type: C-C Bond Formation

pH

2.2 (20 °C, 1100 g/L in H2O)

mp

202 °C

transition temp

flash point >250 °C

solubility

soluble >1100 g/L (decomposition)

bulk density

450‑500 kg/m3

Analysis Note

Assay (argentometric): ≥ 98.0 %
Identity (IR): passes test

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

482.0 °F

Flash Point(C)

> 250 °C


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Absence of sterol regulatory element-binding protein-1 (srebp-1) ameliorates fatty livers but not obesity or insulin resistance inlep ob/lep ob mice.
Yahagi N, et al.
The Journal of Biological Chemistry, 277(22), 19353-19357 (2002)
The membrane anchor of the transcriptional activator SREBP is characterized by intrinsic conformational flexibility.
Linser R, et al.
Proceedings of the National Academy of Sciences of the USA, 112(40), 12390-12395 (2015)
Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11. 2 and 22q13.
Hua X, et al.
Genomics, 25(3), 667-673 (1995)
Chien-Chih Chen et al.
Scientific reports, 7(1), 10901-10901 (2017-09-09)
Atypical antipsychotics (AAPs) are considered to possess superior efficacy for treating both the positive and negative symptoms of schizophrenia; however, AAP use often causes excessive weight gain and metabolic abnormalities. Recently, several reports have demonstrated that AAPs activate sterol regulatory
Mathieu Schmitt et al.
Synapse (New York, N.Y.), 71(9) (2017-04-14)
The therapeutic use of statins has been associated to a reduced risk of Parkinson's disease (PD) and may hold neuroprotective potential by counteracting the degeneration of dopaminergic neurons. Transcriptional activation of the sterol regulatory element-binding protein (SREBP) is one of

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