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8.43377

Sigma-Aldrich

DL-Tartaric acid

for synthesis

Synonym(s):

DL-Tartaric acid

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About This Item

Empirical Formula (Hill Notation):
C4H6O6
CAS Number:
133-37-9
Molecular Weight:
150.09
MDL number:
MFCD00071626
UNSPSC Code:
12352101
EC Index Number:
205-105-7
NACRES:
NA.22
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vapor pressure

<0.1 hPa ( 20 °C)

Quality Level

200

Assay

≥99.0% (acidimetric)

form

solid

autoignition temp.

425 °C

pH

1.6 (25 °C, 100 g/L in H2O)

mp

198-204 °C

transition temp

flash point 210 °C

solubility

215 g/L

storage temp.

2-30°C

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1 of 4

This Item
Y0001572A7986Y0001573
Atovaquone United States Pharmacopeia (USP) Reference Standard

1044651

Atovaquone

Atovaquone European Pharmacopoeia (EP) Reference Standard

Y0001572

Atovaquone

Atovaquone &#8805;98% (HPLC)

A7986

Atovaquone

Atovaquone for system suitability European Pharmacopoeia (EP) Reference Standard

Y0001573

Atovaquone for system suitability

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

EDQM

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

API family

atovaquone

API family

atovaquone

API family

-

API family

atovaquone

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

Analysis Note

Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 198 °C
Melting range (upper value): ≤ 204 °C
Identity (IR): passes test

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

410.0 °F - closed cup

Flash Point(C)

210 °C - closed cup

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    Shirly Grynberg et al.
    The American journal of tropical medicine and hygiene, 92(1), 13-17 (2014-11-06)
    Atovaquone-proguanil (AP) and artemether-lumefantrine (AL) are both treatments for uncomplicated Plasmodium falciparum malaria, but comparative clinical trials are lacking. We performed a retrospective analysis, comparing treatment failure and fever clearance time in non-immune travelers with uncomplicated P. falciparum malaria, treated
    Geoffrey W Birrell et al.
    Antimicrobial agents and chemotherapy, 59(1), 170-177 (2014-10-22)
    4-(tert-Butyl)-2-((tert-butylamino)methyl)-6-(6-(trifluoromethyl)pyridin-3-yl)-phenol (JPC-2997) is a new aminomethylphenol compound that is highly active in vitro against the chloroquine-sensitive D6, the chloroquine-resistant W2, and the multidrug-resistant TM90-C2B Plasmodium falciparum lines, with 50% inhibitory concentrations (IC50s) ranging from 7 nM to 34 nM. JPC-2997
    L M Upton et al.
    Antimicrobial agents and chemotherapy, 59(1), 490-497 (2014-11-12)
    To achieve malarial elimination, we must employ interventions that reduce the exposure of human populations to infectious mosquitoes. To this end, numerous antimalarial drugs are under assessment in a variety of transmission-blocking assays which fail to measure the single crucial
    Sanna R Rijpma et al.
    Malaria journal, 13, 359-359 (2014-09-15)
    Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolism, and excretion. ATP binding cassette (ABC) transport proteins are particularly involved in drug deposition, as they are located
    C Lee et al.
    Journal of dairy science, 98(3), 1885-1902 (2014-12-31)
    This study investigated the effect of metabolizable protein (MP) supply and rumen-protected (RP) Lys and Met supplementation on productivity, nutrient digestibility, urinary N losses, apparent total-tract digestibility of dietary AA, and the efficiency of AA utilization for milk protein synthesis
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