17000

Bromoacetic acid

ReagentPlus^®, ≥99.0%

• Synonym(s): α-Bromoacetic acid, Monobromoacetic acid
• Linear Formula: BrCH₂COOH
• CAS Number: 79-08-3
• Molecular Weight: 138.95
• Beilstein: 506167
• EC Number: 201-175-8
• MDL number: MFCD00002678
• UNSPSC Code: 12352106
• PubChem Substance ID: 329751436
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥99.0% (GC); ≥99.0%
• form: solid
• impurities: ≤1% dibromoacetic acid (¹H-NMR)
• bp: 208 °C (lit.)
• mp: 46-49 °C; 47-49 °C (lit.)
• solubility: chloroform: 10%, clear, colorless
• functional group: bromo; carboxylic acid
• SMILES string: NC(=O)C=C; OC(=O)CBr
• InChI: 1S/C2H3BrO2/c3-1-2(4)5/h1H2,(H,4,5)
• InChI key: KDPAWGWELVVRCH-UHFFFAOYSA-N

Description

Application

Bromoacetic acid is mainly used for the N-terminal bromoacylation of resin bound peptides.
It can also be used:

• To synthesize (Z)-2-(cyclooct-4-en-1-yloxy)acetic acid.
• To synthesize α-bromo-phenylacetamide.
• To convert aromatic thiosemicarbazones to thiazolylhydrazones.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H300,H311 + H331,H314,H317,H400
• Precautionary Statements: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves