32412

4′-Hydroxydiclofenac

VETRANAL^®, analytical standard

• Synonym(s): 4′-Hydroxy Diclofenac, [2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid
• Empirical Formula (Hill Notation): C₁₄H₁₁Cl₂NO₃
• CAS Number: 64118-84-9
• Molecular Weight: 312.15
• Beilstein: 4198042
• MDL number: MFCD01671980
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754193
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: OC(=O)Cc1ccccc1Nc2c(Cl)cc(O)cc2Cl
• InChI: 1S/C14H11Cl2NO3/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(19)20/h1-4,6-7,17-18H,5H2,(H,19,20)
• InChI key: KGVXVPRLBMWZLG-UHFFFAOYSA-N

Description

General description

4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

CYP2C9 metabolite of diclofenac.

Application

4′-Hydroxydiclofenac may be used as an analytical reference standard for the determination of the analyte in rat serum by high performance liquid chromatograph/ultraviolet method.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H315,H318,H335,H410
• Precautionary Statements: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3