79266

Trimethylphenylammonium hydroxide solution

~0.5 M (CH₃)₃N(OH)C₆H₅ in methanol, LiChropur^™

• Synonym(s): Phenyltrimethylammonium hydroxide, TMAH
• Linear Formula: (CH₃)₃N(OH)C₆H₅
• CAS Number: 1899-02-1
• Molecular Weight: 153.22
• Beilstein: 3917033
• MDL number: MFCD00041899
• UNSPSC Code: 41115710
• PubChem Substance ID: 329768356
• NACRES: NA.22

Properties

• grade: derivatization grade ((GC derivatization))
• Quality Level: 100
• form: liquid
• quality: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Esterifications
• concentration: ~0.5 M (CH₃)₃N(OH)C₆H₅ in methanol
• technique(s): gas chromatography (GC): suitable
• impurities: ≤0.2% halides (as chloride)
• storage temp.: 2-8°C
• SMILES string: [OH-].C[N+](C)(C)c1ccccc1
• InChI: 1S/C9H14N.H2O/c1-10(2,3)9-7-5-4-6-8-9;/h4-8H,1-3H3;1H2/q+1;/p-1
• InChI key: HADKRTWCOYPCPH-UHFFFAOYSA-M

Description

General description

Trimethylphenylammonium hydroxide (TMAH) is a methylating reagent.

Application

Learn more in the Product Information

Suitable for the derivatization of amino acids, n-methyl and n-aryl carbamates and fatty acids, clonidine, and substituted phenylureas.

TMAH may be used as a 0.1 mole/litre solution in methanol to determine plasma concentrations of carbamazepine and other anticonvulsant drugs, including phenobarbital, diphenylhydantoin, primidone, and mephenytoin using Gas-Liquid Chromatography.

Other Notes

Reagent for n-methyl and methyl esters.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Sales restrictions may apply

Safety Information

• Pictograms: GHS02,GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H314,H370
• Precautionary Statements: P210 - P280 - P301 + P310 + P330 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 51.8 °F - closed cup
• Flash Point(C): 11 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves