91582

Myristoyl-L-carnitine

analytical standard

• Synonym(s): (2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxotetradecyl)oxy]-1-propanaminium inner salt, L-Carnitine tetradecanoyl ester, C14-Carnitine, Tetradecanoyl-L-carnitine
• Empirical Formula (Hill Notation): C₂₁H₄₁NO₄
• CAS Number: 25597-07-3
• Molecular Weight: 371.55
• Beilstein: 4149853
• MDL number: MFCD28580114
• UNSPSC Code: 41116107
• NACRES: NB.21

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥97.0% (HPLC)
• optical activity: [α]/D -18.0±2.0°, c = 1 in methanol
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤10.0% water
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCC)=O)CC([O-])=O
• InChI: 1S/C21H41NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-21(25)26-19(17-20(23)24)18-22(2,3)4/h19H,5-18H2,1-4H3/t19-/m1/s1
• InChI key: PSHXNVGSVNEJBD-LJQANCHMSA-N

Description

General description

Myristoyl-L-carnitine belongs to the acyl-L-carnitine class of compounds, which are acetylated forms of L-carnitine, derived from the breakdown of amino and fatty acids. The compounds are reported to be used as biomarkers in the diagnosis of carnitine deficiency.

Application

Myristoyl-L-carnitine may be used as an analytical standard to determine the content of the analyte in maize plants using high-performance liquid chromatography coupled to triple quadrupole-LC MS/MS. The exogenous application of carnitine stimulates the transportation of fatty acids into mitochondria, and the possible effect of carnitine on the lipid trafficking between cytoplasm, mitochondrial matrix and the mitochondrial respiration in the leaves of maize grown under normal and cold conditions is investigated.
It may be used as an analytical reference standard in the following:

• Separation and identification of underivatized myristoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
• Determination of the analyte in dried blood samples using high-performance liquid chromatography (HPLC) coupled with electrospray ionization-tandem mass spectrometry (ESI-MS/MS).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable