43424

N-Isovalerylglycine

≥97.0% (GC)

• Synonym(s): N-(3-Methyl-1-oxobutyl)glycine, N-(3-Methylbutanoyl)glycine, [(3-Methylbutanoyl)amino]acetic acid
• Empirical Formula (Hill Notation): C₇H₁₃NO₃
• CAS Number: 16284-60-9
• Molecular Weight: 159.18
• Beilstein: 1766622
• MDL number: MFCD00059629
• UNSPSC Code: 12352209
• PubChem Substance ID: 329756342
• NACRES: NA.26

Properties

• Product Name: N-Isovalerylglycine, ≥97.0% (GC)
• Quality Level: 100
• Assay: ≥97.0% (GC)
• form: powder or crystals
• color: white to off-white
• mp: 87-90 °C
• format: neat
• InChI: 1S/C7H13NO3/c1-5(2)3-6(9)8-4-7(10)11/h5H,3-4H2,1-2H3,(H,8,9)(H,10,11)
• InChI key: ZRQXMKMBBMNNQC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Isovalerylglycine is a byproduct of the catabolism of the amino acid leucine. Accumulation of isovalerylglycine occurs in Isovaleric Acidemia (IVA), an autosomal recessive disorder caused by mutations in the isovaleryl-CoA dehydrogenase gene. The deficiency of this enzyme in the metabolism of leucine leads to the accumulation of a series of isovaleryl-CoA metabolites, such as isovalerylglycine (IVG).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable