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Key Documents

A0231

Sigma-Aldrich

AS 604850

≥98% (HPLC), solid

Synonym(s):

5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione, PI3Kγ inhibitor

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About This Item

Empirical Formula (Hill Notation):
C11H5F2NO4S
CAS Number:
Molecular Weight:
285.22
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

solid

color

off-white

solubility

DMSO: >10 mg/mL
H2O: <2 mg/mL

shipped in

wet ice

storage temp.

2-8°C

SMILES string

FC1(F)Oc2ccc(cc2O1)\C=C3/SC(=O)NC3=O

InChI

1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4-

InChI key

SRLVNYDXMUGOFI-YWEYNIOJSA-N

Biochem/physiol Actions

AS 604850 is a selective PI3Kγ inhibitor

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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