A0781
Aphidicolin from Nigrospora sphaerica
≥98% (HPLC), powder
Synonym(s):
APC
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About This Item
Empirical Formula (Hill Notation):
C20H34O4
CAS Number:
Molecular Weight:
338.48
Beilstein:
4689958
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Quality Level
Assay
≥98% (HPLC)
form
powder
optical activity
[α]27/D +12°, c = 1 in methanol(lit.)
color
white
mp
227-233 °C (lit.)
solubility
ethanol: 1 mg/mL (stable at least a week at 4°C.)
DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
methanol: 10 mg/mL
H2O: insoluble
antibiotic activity spectrum
neoplastics
viruses
Mode of action
DNA synthesis | interferes
storage temp.
2-8°C
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Biochem/physiol Actions
Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Caution
Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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