A1640

Adenosine 5′-O-thiomonophosphate dilithium salt

≥98%

• Synonym(s): 5′-AMPS
• Empirical Formula (Hill Notation): C₁₀H₁₂Li₂N₅O₆PS
• CAS Number: 93839-85-1
• Molecular Weight: 375.15
• MDL number: MFCD00042996
• UNSPSC Code: 41106305
• PubChem Substance ID: 24890572
• NACRES: NA.51

Properties

• Quality Level: 200
• Assay: ≥98%
• form: powder
• storage temp.: −20°C
• SMILES string: [Li+].[Li]SP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C10H14N5O6PS.2Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(21-10)1-20-22(18,19)23;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,23);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: FZXPFDFAEUBVHA-IDIVVRGQSA-L

Description

Application

Adenosine 5′′-O-thiomonophosphate (5′-AMPS) is a 5′-O-thiophosphate which along with adenosine 5′-O-(2-thiodiphosphate) and adenosine 5′-O-(3-thiotriphosphate) can act as inhibitors of phosphohydrolases. AMPS is a substrate for smooth muscle endothelial ecto-5′-nucleotidase. 5′APMS is a stimulator of 5-lipoxygenase activity of rat polymorphonuclear (PMN) leukocytes. Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5′-O-phosphorothioates such as 5′-AMPS to nucleoside 5′-O-phosphates.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H371
• Precautionary Statements: P260 - P264 - P270 - P301 + P312 - P308 + P311 - P405
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 2
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable