A6412

Aflatoxin M₁–BSA Conjugate

• Synonym(s): AFM1-BSA conjugate
• MDL number: MFCD00130364
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 200
• extent of labeling: 4-8 mol aflatoxin M₁ per mol BSA (Lowry)
• storage temp.: 2-8°C

Description

General description

Aflatoxin M1 is a hydroxylated metabolite ofaflatoxin B1. It is found in milk secreted by mammary glands of lactatinganimals, humans, and milk products.

Application

Aflatoxin M1–BSA Conjugate has been used in the indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) with non-labeled aflatoxin M1 and anti-AFM1 antibody.

Biochem/physiol Actions

Aflatoxin M1 is a mycotoxin that elicits both hepatotoxic and hepatocarcinogenic effects leading to immunosuppression in animals. The bioconjugate of aflatoxin M1 (AFM1) with bovine serum albumin (BSA) is useful in the generation of AFM1 specific antibodies which may have immunoassay applications.

Warning

Possibly carcinogenic.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330,H350
• Precautionary Statements: P202 - P260 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves