I0661

(−)-Indolactam V

≥96% (HPLC)

• Synonym(s): (2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
• Empirical Formula (Hill Notation): C₁₇H₂₃N₃O₂
• CAS Number: 90365-57-4
• Molecular Weight: 301.38
• MDL number: MFCD00151197
• UNSPSC Code: 12352200
• PubChem Substance ID: 329815323
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥96% (HPLC)
• form: powder
• color: white
• storage temp.: −20°C
• SMILES string: CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23
• InChI: 1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1
• InChI key: LUZOFMGZMUZSSK-LRDDRELGSA-N

Description

Biochem/physiol Actions

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors.

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors. It is active in the mouse model.

(−)-Indolactam V is naturally present in Streptoverticillium blastmyceticum. It serves as a precursor to the teleocidin class which are alkaloids. It is a the pharmacophore of lyngbyatoxin and teleocidins.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable