L0879

Leu-Leu-Leu

≥90% (elemental analysis), suitable for mass spectrometry (MS)

• Synonym(s): Trileucine
• Empirical Formula (Hill Notation): C₁₈H₃₅N₃O₄
• CAS Number: 10329-75-6
• Molecular Weight: 357.49
• MDL number: MFCD00038309
• UNSPSC Code: 12352202
• PubChem Substance ID: 24896267
• NACRES: NA.26

Properties

• Product Name: Leu-Leu-Leu, ≥90% (elemental analysis)
• Quality Level: 200
• Assay: ≥90% (elemental analysis)
• form: powder
• technique(s): electron microscopy: suitable; mass spectrometry (MS): suitable
• color: white
• storage temp.: −20°C
• SMILES string: CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(O)=O
• InChI: 1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)
• InChI key: DNDWZFHLZVYOGF-UHFFFAOYSA-N

Description

Amino Acid Sequence

Leu-Leu-Leu

Application

Trileucine (Leu-Leu-Leu), an endosome escape moiety, may be used for pH-dependent endosomal membrane disruption to release agents such as antisense oligonucleotides (AONs) inside cells. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves