L4263

Sodium DL-lactate solution

syrup, BioReagent, 60 % (w/w), synthetic, suitable for cell culture

• Synonym(s): DL-Lactic acid sodium salt
• Linear Formula: CH₃CH(OH)COONa
• CAS Number: 72-17-3
• Molecular Weight: 112.06
• Beilstein: 4332999
• EC Number: 200-772-0
• MDL number: MFCD00065400
• UNSPSC Code: 12352207
• PubChem Substance ID: 24896366
• NACRES: NA.75

Properties

• biological source: synthetic
• product line: BioReagent
• form: syrup
• concentration: 27-33% (enzymatic); 60 % (w/w)
• technique(s): cell culture | mammalian: suitable
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(O)C([O-])=O
• InChI: 1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
• InChI key: NGSFWBMYFKHRBD-UHFFFAOYSA-M

Description

General description

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Lactate is one of the main components of Ringer′s lactate or lactated Ringer′s solution.

Application

Sodium DL-lactate solution has been used:

• as a component in DMEM-B to prepare Dulbecco modified Eagle medium (DMEM)-C medium to evaluate the effect of medium composition on in vitro spermatogonial stem cells (SSCs) maintenance
• as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F12 to obtain conditioned media of testicular macrophages
• as a component in non-capacitation medium and TALP medium for sperm preparation and in vitro fertilization
• in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffered synthetic oviduct fluid (SOF) media for oocyte preservation

Biochem/physiol Actions

Lactic acid is produced by lactic acid bacteria (LAB) during carbohydrate fermentation. Different microorganism synthesize different forms of lactic acid such as L(+), D(-) or DL (racemic mixture). It is preferred in food processing and preservation due to its antimicrobial property. Lactic acid is useful as a flavoring and acidifying agent.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves