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Key Documents

M2398

Sigma-Aldrich

Metaproterenol hemisulfate salt

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About This Item

Linear Formula:
C11H17NO3 · 1/2H2SO4
CAS Number:
Molecular Weight:
260.30
EC Number:
MDL number:
UNSPSC Code:
12352107
PubChem Substance ID:
NACRES:
NA.77

Quality Level

originator

Boehringer Ingelheim

SMILES string

OS(O)(=O)=O.CC(C)NCC(O)c1cc(O)cc(O)c1.CC(C)NCC(O)c2cc(O)cc(O)c2

InChI

1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)

InChI key

MKFFGUZYVNDHIH-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

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Application

Metaproterenol hemisulfate salt has been used:
  • as a β2-adrenoceptor agonist to study its effects on adenylyl cyclase stimulation in red blood cell deformability
  • as an adrenergic agonist to study its effects on the stereoselective cell uptake by organic cation transporters in human embryonic kidney cell lines
  • as a bronchodilator to study its effects on the activation of G-protein coupled receptors (GPCR)

Biochem/physiol Actions

Metaproterenol is a β2-adrenoceptor agonist. It shows bronchodilator activity and shows therapeutic effects against bronchitis, asthma, and emphysema.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Inhalation

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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